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Induction is problematic in drug development and an undesirable characteristic for a drug, thus drugs that have Phase II metabolism as their primary route of elimination may be easier to develop

Exercise-induced suppression of PLIN5 therefore limits abnormal LD expansion, reduces TG level and attenuates hepatic lipid accumulation

2.3 Stability studies To investigate the effects of DOXHCl solution on temperature and bright light, it was placed at 40 C for the high-temperature testing and at an illumination of 4,500 lx 500 lx for photostability testing, both of which were sampled on days 0, 5 and 10 for detection of DOX by HPLC

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