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doi:10.1111/jlme.12322

Andrew read more read less 188 photos 6.9K views Jenna Jameson smoking 1 Jenna Jameson smoking 2 Jenna Jameson smoking 3 Jenna Jameson smoking 4 Jenna Jameson smoking 5 Scarlett Johansson smoking 1 Scarlett Johansson smoking 2 Scarlett Johansson smoking 3 Scarlett Johansson smoking 4 Angelina Jolie smoking 1 Angelina Jolie smoking 2 Angelina Jolie smoking 3 Angelina Jolie smoking 4 Angelina Jolie smoking 5 Angelina Jolie smoking 6 Milla Jovovich smoking 1 Milla Jovovich smoking 2 Milla Jovovich smoking 3 Milla Jovovich smoking 4 Milla Jovovich smoking 5 Milla Jovovich smoking 6 Miranda Kerr smoking 1 Miranda Kerr smoking 2 1 2

More specifically, it has been shown that uric acid induces mitochondrial dysfunction and superoxide generation through the activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, thus depleting energy (adenosine triphosphate (ATP)) capacity [17]

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