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Practically, that means IGF-1 LR3 is generally avoided in anyone with a personal or family history that raises cancer concern and it's one more reason this is a medical decision, screened by a provider, not a purchase you make on your own

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[3] That reversibility is a crucial, often-omitted caveat: tesamorelins effect is a maintained pharmacological state, not a one-time fix. We discuss the visceral-fat data and its limits further in our reference on tesamorelins visceral-fat effects and safety profile

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