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Others need optimization to higher doses for best results

Below is a general timeline based on common clinical experience and published research, with the reminder that individual responses vary

Footnotes [1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria: The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment The condition places limitations on self-care, independent living, and social interactions.

This flexibility is a hallmark of metabolic health and is often impaired in individuals with obesity or insulin resistance