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CGRP levels increase in patients with fractures, and it has been postulated that this plays an important role during the inflammatory stage of bone healing and overall during damaged tissue repair [72, 80]

Fraternale et al., 2017), as well as conferring protection against oxidative stress caused by microbial, parasitic and viral infections such as SARS-CoV-2 that causes COVID-19 disease (Morris et al., 2013

Adherent macrophages were then exposed for 24 hours to supplemented DMEM containing various stimuli: lipopolysaccharide at 1 or 100 ng/ml , GHRP-2 at 10^-7 M, and rat ghrelin at 10^-7 M

By contrast, reactive astrocytes modulate Ca 2+ signaling by overexpressing calcineurin, a Ca 2+ -dependent phosphatase that activates inflammation-related genes