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This lack of efficacy was also corroborated by docking studies where these oxysterols exhibited poor binding affinity to B-crystallin and pharmacologically ineffective concentrations [162]

However, the number of articles did not show a constant increase, indicating that few studies have explored the potential of GPXs against biotic stresses, and consequently many questions remain unanswered about their role

One asterisk (*) indicates use of oral vancomycin (standard) or fidaxomicin (standard or extended) and consideration of intravenous bezlotoxumab in patients at high risk for recurrence

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