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Accordingly, individual siRNA inhibition of stearoyl-CoA desaturase 1 ( Scd1 ), Fads2 , or very-long-chain 3-oxoacyl-CoA reductase ( Hsd17b12 ) did not protect against ferroptosis, while pooling all three siRNAs partially protected (Fig

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In these contexts, transplanted mesenchymal stem cells (MSCs) are understood to exert neuroprotective effects primarily through the secretion of a cocktail of neurotrophic factors, modulation of local immune responses, and reduction of neuroinflammation