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Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation

Targeting the IGF-1R signaling pathway is considered a potential breakthrough in anticancer therapy and a number of small molecule inhibitors and monoclonal antibodies targeting IGF-1R, such as BIIB-022, BMS-754807 and Teprotumumab, have been developed and evaluated in clinical trials (113115)

Access this article Similar content being viewed by others References A Li Z Ni J Zhang Z Cai Y Kuang C Yu 2020 Transferrin insufficiency and iron overload in follicular fluid contribute to oocyte dysmaturity in infertile women with advanced endometriosis Front Endocrinol 11 391 A Martines R Masereeuw H Tjalsma J Hoenderop J Wetzels D Swinkels 2013 Iron metabolism in the pathogenesis of iron-induced kidney injury Nature Rev Nephrol 9 7 385 98 Aristizbal B, Gonzlez