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The persistence of these diagnostic delays despite decades of research and awareness campaigns suggests that current clinical approaches are fundamentally inadequate

Beyond infection, G6PD may also play a role in the immunopathology of autoimmune disease

As a result, the search for an infectious viral etiology continued over the years, but a firm causative association has been discounted for most, as no consistent presence of virus, DNA or transcripts has been established in the MS brain that is distinct enough from non-MS controls to provide evidence beyond reasonable doubt (for review see Gilden, 2005

So these are actually skin patches