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Several studies have shown that natural sulfur interventions can improve the integrity of cell membranes, make neurons less vulnerable to damage, lower oxidative stress, reduce neuroinflammation caused by different pro-inflammatory cytokines, and protect cells against excitotoxicity caused by abnormal neurotransmitter release from neurons and astrocytes (8)

HIF-1 transcriptionally upregulates TfR1, leading to increased iron uptake (Yang et al., 2018)

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Ferroptosis is another recently discovered iron-dependent process of programmed cell death, [224] Ferroptosis It is genetically and biochemically distinct from other forms of regulated cell death [225]