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The bigger risk is injecting air while drawing solution back into the syringe

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Selected formulations, incubated at 40C oven, had decomposed over 80% (Figure 1), and the remaining percentage of vitamin B 12 after 2 months in F13 A , F14A1, F14 A2 , F14C1 and F14 C2 was about 0, 4.2, 4.05, 11.3 and 11.2% respectively