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In the current study, the ratio of Firmicutes to Bacteroidetes was significantly higher in WD control mice compared to both groups of mice transitioned from WD to LD (Fig

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Absorption issues: People with mucous membrane lining disorders like Crohn's disease or gluten intolerance (celiac disease) or who have undergone gastrointestinal surgery are more likely to need vitamin B12 supplements as their absorption is impaired

Since B12 is water-soluble, excess amounts are excreted through urine rather than stored in the body, reducing the risk of toxicity