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Several devices are currently marketed, the most widespread being the IQOS (PMI), acronym for I Quit Ordinary Smoking,2,3 by 2022, PMI was promoting it in nearly 60 countries.4 IQOS was first sold in Japan in December 2013,5 which quickly became a best-seller after being advertised on a popular Japanese television show.6 Three years later, in Italy, 329,000 people who had not previously been smokers, used HNB,7 demonstrating that heated tobacco can initiate and maintain an addictive process to nicotine

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The Journey of the Treaty (PDF)