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Several studies have demonstrated increases in the expression of a wide array of genes related to the electron transport chain and fatty acid oxidation reactions upon the activation of PGC-1 ( One possible mechanism underlying the role of mitochondrial biogenesis in CKD was proposed by Mitochondrial Oxidative Stress In addition to energy generation, the mitochondrion is also the major site of cellular ROS production ( On the other hand, mitochondrial antioxidant enzymes appeared to be commonly down-regulated in CKD, indicative of a compromised antioxidant capacity

The protective effect of aged garlic extract on nonsteroidal anti-inflammatory drug-induced gastric inflammations in male albino rats

Another emerging focus is ergothioneine, a unique antioxidant amino acid with its own dedicated transport system (OCTN1) that actively accumulates in tissues prone to oxidative stress, such as the liver, brain, and eyes, he explained

MRPs are also effective delivery systems to enhance stability and bioavailability of several dietary compounds