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Moreover, emerging evidence linking gut-derived factors, such as Akkermansia and free fatty acids, to cognitive decline in elderly individuals with depression suggests the gut-brain axis as a potential target for treating depression-related cognitive impairments

RA was diagnosed based on the American College of Rheumatology (ACR) guidelines and the severity of rheumatoid arthritis (RA) was assessed according to the Disease Activity Score 28 (DAS 28)

When a seizure occurs, brain cell activity speeds up uncontrollably to about four times its normal rate, causing temporary changes in thinking, movement and behavior