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Due to possible surgical complications, as well as risk of sleep apnea, early or late onset abnormal heart rhythms, which in rare cases can be severe, and other potential adverse effects, the use of vagus nerve stimulation has historically been limited to severe and intractable cases

Age-related increase of mitochondrial content in human memory CD4+ T cells contributes to ROS-mediated increased expression of proinflammatory cytokines

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