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Description

In severe cases, B12 deficiency can lead to neurological symptoms, these can include: tremors, seizures, or ataxia (a loss of coordination)

Patients with pernicious anemia are three times more likely to have gastric carcinoma compared to general population

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Oral administration faces hepatic first-pass metabolism, reducing bioavailability to approximately 4050% of subcutaneous routes, but offers convenience for longer-term studies where daily injections create compliance challenges