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External stimuli trigger the production of reactive oxygen species (ROS), leading to oxidative stress and the oxidation of DNA, proteins, and lipids

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E 2( t ) itself is a piecewise linear function found by applying the spline function in Matlab to the data in Panel A of Figure 2 for estradiol as a function of day of the cycle for the average woman

is partly supported by the Faculty Postdoctoral Fellowship Scheme of the Chinese University of Hong Kong