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The study on this also looked at other NSAIDs, including aspirin and ibuprofen, and found that they did not increase the risk of blood cancers.[ref] Genotype report: Acetaminophen and liver damage The genotypes section of the article includes genetic variants associated with liver problems from acetaminophen, but if you have any concerns about your acetaminophen use, talk with your healthcare provider

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Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial