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Alterations of oligodendrocyte and myelin energy metabolism in multiple sclerosis

Statistically, in healthy individuals, about 12 h after ED ingestion, there is an increase in systolic blood pressure by 610 mmHg, diastolic blood pressure by 36 mmHg, heart rate by about 37 beats/minute, and QT interval prolongation up to 2225 ms

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Results Increased severity of liver injury and mortality of mice with hepsin deficiency during the early period after acetaminophen exposure To investigate the potential physiological role of endogenous hepsin in the early response to APAP-induced liver injury, we analyzed hepsin expression in wild-type mouse liver lysates following APAP treatment using western blotting (Fig