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They were contacted and were given the Global Response Assessment questionnaire to evaluate the patients perceptions of treatment effectiveness.64 (Peters et al., 2008) See Table 1 for the Global Response Assessment Scale

It was first identified by Loren Pickart in 1973 and the research on it has been building ever since

It has long been known that ROS play an important part in the innate immune system as a microbicidal compound produced by NADPH oxidases (NOXs) in phagosomes of phagocytic cell types such as macrophages and neutrophils [18]

However, the longterm and highdose treatment with NAC failed to improve lung function or reduce the annual rate of total exacerbations [194]