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A study in 2019 in the Journal of Human Reproductive Sciences found that oxidative stress is associated with decreased sperm motility, increased sperm DNA damage, and an increased risk of miscarriage and genetic abnormalities

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Additionally, iron-activated ERK/MAPK pathways may contribute to tau phosphorylation and neuroinflammatory cytokine release, suggesting a potential feedback loop between iron dysregulation, tau pathology, and inflammation (125, 126)

Topical or intraperitoneal application of NAC has been found to delay cataract formation in rats by increasing glutathione synthesis and suppressing oxidative stress