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The human hepatocellular carcinoma cell line (HepG2) was cultured in high-glucose DMEM containing 10% FBS

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In a phase 2 dose-finding trial, once-weekly Cagrilintide produced clinically meaningful weight loss about 10.8% at the 4.5 mg dose over 26 weeks with gastrointestinal effects the most common adverse events [1]

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Currently, there are no effective treatment methods to prevent the occurrence of AKI

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Metabolic changes in tamoxifen-resistant MCF-7 cell lines were manifested with the increase of glutathione, xanthine, and other metabolites involved in antioxidant pathways along with their dysfunctional genes' expression

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