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The societal effect of this disorder is enormous both in monetary costs and in quality of life

These findings support a personalised approach, where absorption efficiency may be more relevant than absolute dosage

The accumulation of ROS can generate and promote this apoptotic equilibrium

Incubation of NFT with cell or tissue homogenates, microsomal preparations, or isolated mitochondria revealed one-electron reduction of NFT to yield an NFT radical anion ( NFT ) by flavoprotein-reductases such as xanthine oxidase, aldehyde dehydrogenase, thioredoxin reductase, cytochrome b 5 reductase, and cytochrome P450 reductase (CYPOR) (Miller et al