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For this reason, these patients have a major risk to evolve a more severe form of COVID-19 [149]

Molecular mechanisms of insulin resistance in type 2 diabetes mellitus

At the lung level, the infection is associated with the recruitment of monocytes differentiating into pro-inflammatory macrophages (M1), which produce a large amount of pro-inflammatory cytokines such as interleukins (IL1, IL6, IL18) and chemokines

Involvement of interleukin-6-regulated nitric oxide synthase in hemorrhagic cystitis and impaired bladder contractions in young rats induced by acrolein, a urinary metabolite of cyclophosphamide