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While inhalation therapy has many benefits, it also has some drawbacks

This is in contrast to a prebiotic, which is typically a nondigestible food ingredient that may benefit the host intestinal microflora by stimulating growth and activity of a few selected organisms [163]

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In the course of this reaction, in neutral pH, metals (Fe or Cu) interact with carbonate and hydroperoxides resulting in the formation of carbonate radical anion CO 3 , which may dominate over the hydroxyl radicals when the concentration of bicarbonate is higher than 100 M