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Description

No human study has tested these combinations

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(Scientific Reports, 2021) reported that NNMT inhibition plus a lean-diet substitution lowered body weight, fat mass, and liver fat beyond either intervention alone

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2015 NNMT consumes SAM as a methyl donor, competing with DNA and histone methyltransferases

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[2] In DIO mice, 5-Amino-1MQ was reported to reduce body weight and white adipose mass and to lower plasma cholesterol, without a measured change in food intake

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