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Another example where GCLC and GS are coordinately regulated but GCLM is unchanged is found in liver-specific retinoid X receptor (RXR) knockout mice (Wu et al., 2004)

The organic phase comprises Span 60 and LS dissolved in a little bit of absolute ethanol and stirred at 1000 rpm and a temperature of 70 C until a clear solution is obtained

The acute form of the disease is characterized by the sudden onset of cardiac insufficiency, while the chronic form results in moderate-to-severe heart enlargement with varying degrees of cardiac insufficiency (52)