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Advances in molecular biology have further enhanced our understanding of G6PD deficiency, and now over 160 different gene mutations or mutation combinations have been identified

DCruz AA et al (2018) The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils

This biological link is supported by common underlying pathways, such as hepatic and systemic insulin resistance, atherogenic lipid profiles, hypertension, and increased expression of pro-atherogenic, pro-coagulant, and pro-inflammatory factors [75]

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