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Frontiers in Bioengineering and Biotechnology, 9 , Article 677576

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Huang Z., Liu Y., Qi G., Brand D., Zheng S.G

While some treatments like permanent skin whitening tablets and injections offer long-lasting results, maintenance treatments may be necessary to sustain the desired skin tone

To chemoenzymatically synthesize selective cathepsin C inhibitor E-64c hydrazide, a large-scale 40-ml reaction in 50 mM sodium phosphate buffer (pH 8.0) containing 5 mM ()- t -ES, 2.5 mM l-norleucine ( a3 ), 2.5 mM tryptamine ( b44 ), 2.5 M Cp1B and 2.5 M Cp1D was carried out at 30 C for 16 h