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It acts as a signaling molecule that: Activates tissue repair pathways Stimulates collagen and glycosaminoglycan synthesis Promotes angiogenesis Modulates inflammation via NF-B suppression When endogenous levels fall, regenerative capacity falls in tandem

Reprod., 2018, doi: 10.1093/humrep/dey038

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B12 is required for the synthesis of red blood cells, growth and a childs development, maintaining the nervous system and synthesis of DNA during cell division, which is especially important in regions of rapid cell division such as bone marrow (red blood cell formation)