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Body composition / lean mass Studied as a GH secretagogue for effects on lean mass and body composition

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Growth Restoration in GHRH-Knockout Mice Alba et al., American Journal of Physiology Endocrinology and Metabolism (2006) Alba and colleagues evaluated CJC-1295 in a GHRH-knockout mouse model in which native GHRH gene expression has been ablated, producing severe growth failure that is not normalized by twice-daily injections of standard short-acting GHRH analogs