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Nevertheless, some clinical-pathological studies(postmortem brain tissue samples from AD patients) has revealed significant limitations in this theoretical framework ( Given these limitations, the establishment of a conceptual model capable of integrating multiple pathological processes and elucidating their spatiotemporal dynamics becomes imperative

The commercial material is synthetic and is not an established circulating human pineal hormone

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Yang Z, Du X, Wang A, Zhao Y, Xia Y, Shi L, et al