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Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR)
Phorbol 12-myristate 13-acetate (PMA)
Bafilomycin A1 is a potent inhibitor of cellular autophagy either by blocking autophagosome-lysosome fusion or by blocking lysosomal degradation
and has lower selectivity over PKA
Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit 210344-95-9 Forms a complex with FKBP12Nicotinamide phosphoribosyltransferase (Nampt; pre B cell colony enhancing factor; PBEF; Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate limiting NAD+ biosynthetic enzyme is well established, the physiological role of