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Cognitive decline and gait disturbance are often observed simultaneously in SVD patients, also known as motoric cognitive dysfunction, but its shared underlying neural basis remains not fully understood

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The metabolites were annotated using the KEGG database and statistical analysis was performed using the statistical software R (R version R-3.4.3), Python (Python 2.7.6 version), and CentOS (CentOS release 6.6)

However, further translational research is required to determine its full mechanistic scope and potential therapeutic applications