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Breach in intestinal permeability is mediated by the microbiota To further examine the link between the arthritis-related immune response, changed microbiota and intestinal epithelial barrier dysfunction, we applied different immunization protocols including (i) arthritogenic collagen type II + complete Freunds adjuvans (CII + CFA), (ii) denaturized CII + CFA (deCII + CFA) and (iii) CII without CFA (CII)

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The mounds, craters and caves that punctuate these sites, along with others dispersed both through the US and other countries that experienced nuclear testing and activity, testify of the great sacrifices that were inflicted upon territories that, realistically, will never return to their original condition