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Seek medical attention promptly if you experience symptoms that could suggest serious underlying conditions, including: Unexplained weight loss or persistent fatigue Jaundice (yellowing of skin or eyes), abdominal pain, or swelling Easy bruising or bleeding , or unusual skin rashes Night sweats , fever, or enlarged lymph nodes Reduced urine output , significant swelling in legs or ankles Persistent itching without obvious skin cause These symptoms may indicate liver disease, haematological disorders, or renal impairmentconditions that can elevate B12 and require specialist assessment
Poor growth rates and ill thrift may be seen in affected animals
Metformin is one of the most commonly prescribed drugs for type 2 diabetes and is well known to be associated with vitamin B 12 deficiency [19, 21, 22]
The dose for IV vitamin B12 therapy can range from 1,000 to 5,000 mcg
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