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For instance: Sub-toxic doses of nsPEF activate autophagy as a compensatory mechanism to repair membrane damage, but prolonged exposure increases cell death while concomitantly reducing autophagy markers ( Notably, nsPEF can also exert cell cycle-specific effects on tumor cells, such as inhibiting the proliferation of S-phase cells without significantly affecting their viability ( Collectively, these studies reveal the potential of PEFs to exert multi-faceted anti-tumor effects by inducing apoptosis, modulating autophagy, triggering ferroptosis, activating other RCD pathways, and potentially synergizing with chemotherapeutic drugs ( Figure 2 )

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This would remove an enormous financial and time burden from the NHS, and GP Practices and would allow the panic to, at least partially, subside in hundreds of thousands of people in the UK