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[114] found that the mitochondrial aberrations, fission, oxidative stress, and cell apoptosis were increased, while mitochondrial respiration and fusion were decreased in CSE-induced rat lung microvascular endothelial cells (RLMVECs)

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The activity of respiratory chain complexes I (NADH dehydrogenase) and III (cytochrome bc1 complex) is significantly reduced in HCC cells, leading to decreased electron transport efficiency and reduced ATP production 44