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The digestive enzymes within lysosomes function optimally at an acidic pH, meaning they require a permanent supply of protons

In the emerging field of proteomics, an essential step in understanding protein structure and function is to determine which proteins interact with each other, thereby identifying the relevant biological pathways

Abnormal iron metabolism is a significant trigger for ferroptosis, with iron-related proteins including transferrin receptor protein 1 (TfR1), ferritin (FTH and FTL), and iron export proteins playing essential roles in iron homeostasis

Results from HSL-null mouse models suggest, therefore, that adipocytes may harbor additional, less active DAG lipases, as well as TAG lipases