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Using this approach, we discovered a novel role for the melanogenesis-associated transcription factor, or MITF, in repressing the expression of innate immune genes within cells of the melanocyte lineage in mice. The importance of this repression is revealed in animals that have a predisposition for hair-graying

Its primary role is antioxidant protection

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American Journal of Physiology-Gastrointestinal and Liver Physiology