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Kovalzon and Strekalova, reviewing the field in 2006, described DSIP as a still unresolved riddle and argued that the link between DSIP and sleep had never been further characterized, in part because of the lack of isolation of the DSIP gene, protein and possible related receptor (Kovalzon & Strekalova, 2006)

(46) analysed cerebral cortex and hippocampal mitochondria from hyperglycaemic and recurrently hypoglycaemic animals and found that cerebral cortical mitochondria exhibited high levels of MDA and -tocopherol and increased glutathione disulphide reductase activity

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Getting the shoulder moving as soon as possible is important, however, this must be balanced with the need to protect the healing tissues