And an interim analysis of a phase II Study of the glutaminase inhibitor CB-839 in combination with Azacitidine in advanced myelodysplastic syndrome (MDS) showed CB-839 at a dose of 600 mg BID orally continuously daily is safe and well tolerated in combination with azacitidine in patients with advanced MDS with an acceptable safety profile [92]
Pan D, Sanyal N, Schmieder AH, Senpan A, Kim B, Yang X, Hu G, Allen JS, Gross RW, Wickline SA, Lanza GM
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