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Introduction Iron metabolism Iron, which has the highest content of all essential trace elements in the human body, plays a critical role as a biologically essential component of every living organism ( via the production of reactive oxygen species (ROS), including hydrogen peroxide (H 2 O 2 ), hydroxyl radicals (HO), superoxide anions (O 2 ), and other reaction intermediates with free radical properties ( 2 O 2 in it, thereby generating extremely reactive HO

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Endogenous triggers, such as the acidic pH of the TME or elevated intracellular glutathione levels, can activate drug release, leveraging the NP's cleavable linkers or redox-sensitive conjugates [189]

Uncover the hidden clues your body has been trying to tell you, including an in-depth look at MTHFR mutations