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It is an extremolyte , a small stress-protection molecule that protects microorganisms living under extreme conditions such as salt lakes, hot springs, arctic ice, the deep sea, or deserts

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In summary, the discovery of ferroptosis expands our understanding of CD in CCVDs, and targeting ferroptosis will provide a new strategy and broaden thoughts for the prevention and treatment of CCVDs

When glutamate stimulates N -methyl-d-aspartate (NMDA) receptors on the surface, it activates a GTP-binding protein called Dexras1, which in turn stimulates DMT1, allowing cells to absorb more iron (316, 317)