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Because AOD-9604 does not bind to growth hormone receptors in liver, muscle, or adipose tissue, it cannot trigger the metabolic pathways that mediate growth hormones counter-regulatory effects on glucose metabolism

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Study to Assess Safety and Immune Response of Stage IIB-IV Resected Melanoma After Treatment With MAGE-A3 ASCI (Mel55) ClinicalTrials.gov Identifier: NCT01425749 ( Vaccine Therapy and Interleukin-12 in Treating Patients With Metastatic Melanoma ClinicalTrials.gov Identifier: NCT00054535 ( Gutzmer R, Stroyakovskiy D, Gogas H, Robert C, Lewis K, Protsenko S, et al