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The induced Tregs are predominantly the IL-10 + cytotoxic-T-lymphocyte-associated antigen-4 (CTLA4) high Helios-subset with potent immunosuppressive activity, and they can migrate to extraintestinal organs to suppress systemic inflammation

(I) The relevant mechanisms involved in each step of the intracellular GSH exhaustion process need to be further explored, and the biological effect of cancer cells after GSH depletion remains to be elucidated

The optimal harvesting procedure should be worked out once the composition of the zones of banded material (A-D in Figure 1) and the pellet has been verified

Similar PCA and t-SNE results were demonstrated in the GEO and TCGA cohorts (Fig