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EGFR activation leads to induction of MAPK signaling (via p38, ERK1/2) and the activation of c-Fos (Naglik et al., 2019), ultimately triggering the production of inflammatory mediators such as G-CSF and GM-CSF (Nikou et al., 2022), and the activation of the NLRP3 inflammasome leads to the release of IL-1 (Rogiers et al., 2019)

The safety of an ingredient depends on its specific properties, not its origin

Data processing Selected diffraction patterns were processed with programs from the MRC suite 52 in order to perform indexing and retrieve integrated, background corrected intensities

Up-regulation of the human -glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element