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The medullary thyroid carcinoma signal observed in rodent studies at supratherapeutic doses has not been confirmed in human populations across approximately eight years of post-market surveillance, but the contraindication in patients with relevant personal or family history remains appropriate

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Hypertrophy + hyperplasia Animal-model research shows IGF-1 LR3 drives both fibre growth (hypertrophy) and new fibre formation (hyperplasia) - distinct from most anabolic agents

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