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Key Research Findings: In early studies, Retatrutide has demonstrated significant body weight reduction, in part due to increased thermogenesis and lipolysis (Abouelmagd & Abdelrehim

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Heijer JMD, Kruithof AC, van Amerongen G, de Kam ML, Thijssen E, Grievink HW, Moerland M, Walker M, Been K, Skerlj R et al (2021) A randomized single and multiple ascending dose study in healthy volunteers of LTI-291, a centrally penetrant glucocerebrosidase activator

While the peptide does not increase IGF-1, caution is warranted given the theoretical relationship between growth factors and cancer progression